211-1899/24-2H PhD fellowship in Molecular Biology

PhD fellowship in Molecular Biology
Department of Biology
Faculty of SCIENCE
University of Copenhagen

Department of Biology, Section for Biomolecular Sciences invites applicants for a PhD fellowship in intracellular protein quality control and degradation. The start date is December 1st 2024 or as soon as possible thereafter.

The project
The PhD project focuses on the mechanisms involved in specific ubiquitin and proteasome dependent degradation of structural destabilized missense protein variants linked to human genetic disorders. The project will involve a broad range of molecular biological techniques, including various high throughput screening technologies with human cell lines and yeast, FACS, and NGS.

Who are we looking for?
We are seeking highly motivated and strong applicants with a Masters’ degree in biochemistry, molecular biomedicine, molecular biology or similar fields. In addition, prior research experience with one or more of the following techniques/areas is needed:

• High throughput screening
• Deep mutational scanning
• Yeast genetics
• Cell and molecular biology
• The ubiquitin-proteasome system

We are looking for the following qualifications

• Professional qualifications relevant to the PhD projects
• Relevant publications
• Relevant work experience
• Other relevant professional activities
• Curious mind-set with a strong interest in research
• Good communication skills and team-oriented work ethics

Our group and research- and what do we offer?
The PhD student will work in the group of Prof. Rasmus Hartmann-Petersen located in the Department of Biology, University of Copenhagen, in central Copenhagen. The group is a member of the interdisciplinary and collaborative research environment at the Linderstrøm-Lang Centre for Protein Science. The PhD student will work in a focused team as well as with scientists from a number of disciplines, and engage in collaboration with other partner laboratories. The group is international and a good level of spoken and written English is essential.

The PhD programme
Depending of your level of education, you can undertake the PhD programme as a three year full-time study within the framework of the regular PhD programme (5+3 scheme), if you already have an education equivalent to a relevant Danish Master’s degree.

Qualifications needed for the regular programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. biochemistry, molecular biomedicine, or molecular biology. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.

Terms of employment in the regular programme
Employment as PhD fellow is full time and for maximum 3 years.

Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.

Responsibilities and tasks in the PhD programmes

• Carry through an independent research project under supervision
• Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
• Participate in active research environments, including a stay at another research institution, preferably abroad
• Teaching and knowledge dissemination activities
• Write scientific papers aimed at high-impact journals
• Write and defend a PhD thesis on the basis of your project

Application and Assessment Procedure
Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.

Please include:

1. Motivated letter of application (max. one page)
2. Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position
3. Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
4. Publication list (if possible)
5. Reference letters (if available)

Application deadline:
The deadline for applications is Sunday September 15th 2024, 23:59 GMT +2.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.

The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

Interviews with selected candidates are expected to be held in week 41.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor, Prof. Rasmus Hartmann-Petersen, [email protected], Phone: +45 26941565.

General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://science.ku.dk/phd/

The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.