Computational postdoc position to study neurodevelopmental mechanisms in psychiatric disorders at BRIC

We are looking for a highly motivated and dynamic postdoc for a 3-year position, who will join a team of molecular and cellular biologists and computational scientists studying human neurodevelopmental disorders to commence 15 May 2025

Information on the department can be found at: https://www.bric.ku.dk/



Our research
Our group studies mechanisms that are responsible for neuronal specification, positioning and circuit formation during prenatal and postnatal brain development, and how these mechanisms are impaired in neurodevelopmental disorders such as schizophrenia, epilepsy, autism. We analyse mouse models of neurodevelopmental disorders and human tissue to identify those neurons that are affected in a particular disorder, and how dysfunction of affected neurons contribute to brain circuit malformation and underlie cognitive impairment in human patients. Our work is highly interdisciplinary, from high-throughput analyses of single neurons in human and mouse tissues to functional studies of disease relevant genes in model systems. Importantly, we have international network of collaborators for studying human brain disorders by variety of frontline technologies and cooperate with several Hospitals for most efficient transition from basic to translational studies.



Your job
You will investigate the mechanisms contributing to impaired brain function in psychiatric disorders identified in human patient tissues, in animal models, and in human cellular systems. You will utilize data from various modalities of single cell and spatial omics and will integrate them to determine molecular mechanisms of brain dysfunction and develop novel therapeutical targets.



Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

• You have a PhD in intersection of Neuroscience and Computation
• You are highly experienced in computational analysis of single-cell omics data
• You have an active interest in studying developmental mechanisms in psychiatric disorders
• Proficient communication skills and ability to work in teams
• Excellent English skills written and spoken

Desirable experience and skills:

Experience/knowledge in differential analysis using single-cell transcriptomics data



Place of employment

The place of employment is at BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and access to state-of-the-art core facilities.



Terms of employment
The average weekly working hours are 37 hours per week.



The position is a fixed-term position limited to a period of 3 years. The starting date is 15 May 2025 or after agreement

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 38,700 DKK/approx. 5,100 EUR (April 2025 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the Job Structure for Academic Staff at Universities 2020.



Questions
For further information please contact Professor Konstantin Khodosevich on e-mail: [email protected]; www.sund.ku.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).



Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Deadline for applications: 11 March 2025, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.



The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.



Interviews are expected to be held in week 13-14

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.