MASH Principal Scientist

Are you an experienced and highly motivated scientist? Would you like to drive our efforts in the discovery of novel therapeutic molecules in metabolic dysfunction-associated steatohepatitis (MASH) as part of a world-class pharmacology research team within Obesity & Liver Disease? 

Then please read further! We are seeking a talented Principal Scientist to be part of Novo Nordisk and participate in changing the quality of life for millions of people with cardiometabolic diseases. 

The position

You are a disease expert within MASH and liver fibrosis with a strong background in metabolism and drug discovery. The role will require leadership and participation in drug discovery project teams, cross-functional planning of complex pharmacology studies, and other project team activities related to new targets and MASH in general. Mentoring and supervision of technical/junior staff is an integral part of the job. You will join a global team of highly skilled professionals, and you will work with CROs and academic collaborators in order to provide project teams with critical data and support. 

In addition, you will: 

• Lead scientific excellence in MASH and liver fibrosis biology to actively engage in target discovery, innovation, and project progression.  
• Design and conduct key experiments to validate human relevance and explore pharmacokinetics, pharmacodynamics, and mode of action, both internally and externally always applying the highest scientific standards and assessing available translational tools. 
• Develop and implement new models, methods, and technologies for in vivo/ex vivo testing of biological activity of new targets.
• Be responsible for writing protocols, data analysis, interpretation, record keeping, reporting, and communication of results.
• Communicate complex multidisciplinary topics to Liver Disease Research (in vitro), Translational Medicine, Bioinformatics, Global Drug Discovery Leadership and project teams as well as relevant governance bodies. 
• Collaborate with internal stakeholders within a matrix environment as well as external scientific advisors and academic centres of expertise.

Qualifications
The ideal candidate is highly skilled in establishing, optimizing, validating, and running MASH studies in rodents and has experience with translational aspects of the model(s). A solid scientific network, as well as international experience, will be highly valued.

In addition:

• You hold a Ph.D. within the cardiometabolic field and have significant post-graduate experience. Preferably at least 5 years of experience in pharma R&D.
• Experience with other cardiometabolic diseases, including diabetes, obesity, cardiovascular disease, and renal disease is an advantage. 
• Strong scientific knowledge and a profound focus on translation is essential as well as a proven scientific track-record of contributing to the delivery of high-quality drug discovery candidates into clinical development is a huge advantage. 

Furthermore, to your scientific profile, you are a dedicated, open-minded, and innovative team player with good collaboration and problem-solving skills, highly proficient in spoken and written English. 

About the department
The department is part of Global Drug Discovery, which specialises in the discovery of biological medicines for the treatment of diabetes, obesity, haemophilia, chronic liver disease, chronic kidney disease, and cardiovascular diseases. We always strive for excellence and continuously develop our expertise to stay ahead - both as a company and as individuals.  We believe that innovation and creativity thrive in a healthy and engaging working environment. Therefore, we give you the opportunity to bring your personal ambition and passion to work to improve the quality of life of the patients.

Working at Novo Nordisk

At Novo Nordisk, we don't wait for change. We drive it. We're a dynamic company in an even more dynamic industry, and we know that what got us to where we are today is not necessarily what will make us successful in the future. We are anchored on scientific innovation through the power of our diverse differences. We embrace the spirit of experimentation and strive for excellence without fixating on perfection. We never shy away from opportunities to develop, we seize them. From research and development, through to manufacturing, marketing, and sales – we are all working together to advance patient care.

Contact
For further information, please contact Sanne Skovgård Veidal, Director Obesity & Liver Pharmacology at [email protected]. 
 
Deadline
5 January 2025

Please note that applications will be reviewed continuously, thus the advert may close prior to the indicated deadline.

You do not need to attach a cover letter to your application but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo to your CV.
 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.