One PhD position in bioorganic chemistry is available in the group of Professor Jasmin Mecinovic at the Department of Physics and Chemistry, University of Southern Denmark.
Project background
Posttranslational modifications on nucleosomal core and linker histone proteins are central to transcriptional regulation in eukaryotes and are thus of fundamental importance to complex life. In contrast to advanced biomolecular understanding of core histones, the basic molecular knowledge on linker histones is currently limited. As a PhD student, you will work on the Novo Nordisk Foundation NERD-funded project aimed at developing innovativechemical tools that will enable precise elucidation of roles of linker histones and their posttranslational modifications in the chromatin structure and function. You will apply modern bioorganic chemistry and chemical biology approaches, ranging from peptide and protein synthesis to enzyme assays and protein binding studies, in investigations of biologically important linker histones.
Research group
The research in Mecinovic group applies chemical principles and techniques to understand the underlying molecular origin of fundamental biomolecular processes that play essential roles in human health and disease. The group is international, cross-disciplinary and gender-balanced. The successful candidate will receive excellent training, mentoring and career development support.
Qualifications
Specific Requirements
Website: https://www.sdu.dk/en/forskning/mecinovic-group
The Department of Physics, Chemistry and Pharmacy is one of four departments at the Faculty of Science, SDU and is located in Odense. The Department of Physics, Chemistry and Pharmacy is a department focused on basic research. We are happy to move beyond traditional disciplines and work to develop new technologies and sciences across physics, chemistry, pharmacy, mathematics, computer science and biology. The department’s research thus contributes to new knowledge and solutions with applications in the areas of climate, environment, energy, and health.
The Ph.D. candidate will be part of the Section for Chemistry and Pharmacy.
The deadline for applications: 10 January 2025.
Please see the full call, including how to apply, on www.sdu.dk
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