Postdoc in Computational Biology

The Genome Biology Research Unit at the Department of Molecular Medicine (IMM) invites applications for a position as postdoc in Computational Biology in the laboratory of DNRF Chair and Novo Nordisk Faculty Professor Vijay Tiwari (https://www.tiwarilab.org/).

The position is available - initially for six months - from April 1, 2025, or as soon as possible thereafter - with the possibility of extension.

Tiwari lab employs cutting-edge single-cell and spatial omics technologies with bioinformatics and machine learning to decipher principles of gene regulation. In this project, the candidate will develop new computational strategies to identify human genetic variation linked to cell fate changes in neurodevelopmental disorders and cancer. The candidate can use and combine single-cell ATAC-seq, single-cell RNA-seq, spatial gene expression, and whole-genome sequencing (with long reads) data. The candidate will get the opportunity to explore new analysis methods using deep learning. Depending on the interest, it is also possible to be involved in the wet lab, to perform single-cell sequencing and other experiments.

To learn more, please refer to the selected publications from the Tiwari lab:

Molecular Cancer, 2024 in press; JCI Insight, 2024, Nov 14:e184518; Science Advances, 2024, Jun 7;10(23):eadn1640; EMBO Mol Medicine, 2024, Apr; 16(4):823-853; Nature Communications, 2024, in press;  npj Precision Oncology, 2024, Mar 12;8(1):64; Nature Cell Biology, 2022, 24, 1265–1277; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23):4380-94; The EMBO Journal, 2015 Aug 13;34(16):2162-81; Genome Research, 2015 Sep;25(9):1309-24; Nature Communications, 2013, Sep 27; 4:2478; Cancer Cell, 2013, 23, 768-783; PNAS, 2012 Apr 17;109(16): E934-43; Nature Genetics, 2012 Jan; 18;44(1):94-100;  Nature, 2011 Dec 14;480 (7378):490-5.     

You will

• Employ new computational strategies to link human genetic variation with cell-fate changes in neurodevelopmental disorders
• Analyze bulk, single-cell and multi-omics datasets
• Lead projects on gene regulatory mechanisms that contribute to the development and disease
• Support research and development activities within the group
• Maintain accurate and detailed records of research activities 
• Support the group leader in everyday routines including training new group members
• Support the group leader in grant applications and management 
• Collaborate with internal and external partners
• Engage in teaching and supervision as required

Expectations of qualifications

• PhD in Bioinformatics, Computer Science, Physics, Engineering, Bio-engineering, or equivalent
• Excellent track record in Bioinformatics with at least one first-author publication, accepted or submitted
• Experience with machine learning will be a plus (e.g., Tensorflow/Keras/PyTorch). 
• Experience with software containers and/or NextFlow is a plus. 
• Programming experience is required (Python, R). 
• Previous experience in Genomics data analysis
• Strong analytical, organizational, and record-keeping skills
• Interest in working in a multidisciplinary and multicultural team 
• Willing to collaborate with internal and external collaborators as well as support group members
• Experience and interest in supervision

We offer 

• The possibility to engage in high-impact, multidisciplinary research
• A stimulating, diverse and international research environment 
• An initial contract for six months, with the possibility of long-term extension 
• Advanced training opportunities 
• Highly motivated research team and international collaborations
• Access to state-of-the-art equipment and facilities
• A supportive scientific and social network, including mentoring and career development
• A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
• Support with practical, social, and legal aspects (e.g. housing, visa, tax etc.) through our international staff office (ISO) and the department

The Department of Molecular Medicine (IMM)

IMM aims to generate new knowledge on the function of the human body and disease mechanisms, thereby contributing to improved human health. IMM hosts an interdisciplinary group of experts in cancer biology and neurobiology and is in close proximity to the experts in genomics, proteomics and chromatin biology. Such a promising environment elicits translational collaborations with clinical practice and research toward understanding mechanisms underlying the pathophysiology of various human diseases.

Further information

Further information can be obtained by e-mail to Professor Vijay Tiwari at [email protected]

Application deadline

January 30, 2025, at 23.59 hrs. CET

Salary and terms of employment

The successful applicant for the postdoc position will be employed in accordance with the agreement between the Danish Ministry of Finance and AC (the Danish Confederation of Professional Associations).

Application

Applications must be submitted electronically using the link “Apply now” - see below.

We strongly recommend that you read How to apply for a position at SDU before you apply.

Only applications written in English will be accepted for evaluation.

The application must include (as PDF files) (please note that the application (the motivation letter) and CV must not exceed 10 MB in total):

• a motivation letter
• a detailed CV including contact information
• degree certificates (inclusive of Ph.D.-diploma)
• a complete and numbered list of publications

Please note that all the above-mentioned information must be included in the application. Incomplete applications will not be assessed.

If you experience technical problems, you must contact [email protected].   

Applications may be shortlisted. 

Living and working in Denmark

Foreign applicants will be offered Danish language training  as part of the employment. 

The International Staff Office (ISO) at SDU provides a variety of services for new employees, guests and people who are considering applying for a job at the University of Southern Denmark.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.