Postdoc in Regulation of Enteroendocrine Lineage Specification at reNEW

The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, is looking for Postdoctoral candidate to join the Jensen group starting 1 February 2025 or upon agreement. You will be part of a project studying the regulation of Enteroendocrine Lineage Specification. The postdoctoral researcher will work with the team of Professor Kim B. Jensen at reNEW, Copenhagen.

The Center:
The Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, is an international consortium of three leading research institutions; the University of Copenhagen, Denmark, Murdoch Children’s Research Institute in Melbourne, Australia, and Leiden University Medical Center in Leiden, The Netherlands. The Mission of reNEW is to bring together research excellence to harness the therapeutic potential in stem cell medicine. For this, researchers within reNEW address fundamental questions in stem cell and developmental biology and aim to translate research findings to products that will help patients with incurable disorders such as congenital kidney disorders, chronic ulcerative disorders, neurological disorders, and diabetes.

Information on the department can be found at: https://renew.ku.dk

Our research
In the Jensen group, we wish to understand how adult intestinal stem cells are specified during development, how their behaviour is regulated during steady state homeostasis, and how they dynamically change during tissue regeneration. This has provided us with insights (e.g. Yui et al., 2018, Cell Stem Cell; Guiu et al., 2019, Nature; Schweiger et al., 2022, Gastroenterology; Pikkupeura et al., 2023, Science Advances; Hansen et al., 2023, Science Advances) that we are now exploiting to direct lineage differentiation in the intestinal epithelium. We are a highly interdisciplinary and international team with established collaborators across the world as well as within the major hospitals in Copenhagen region. This provides the ideal environment for bridging fundamental research with clinical practice.

More Information can be found at: https://renew.ku.dk/research/jensen_group/

Job description:
We are seeking an enthusiastic and outstanding post-doctoral candidate with a strong background in stem cell biology. The candidate will implement cutting-edge high-content screens to direct epithelial differentiation along the enteroendocrine lineage.

Qualifications:

• A PhD degree in life sciences
• Documented hands-on experience with the intestinal epithelium and intestinal epithelial organoid cultures
• Background in genetics, cell biology, and bioinformatics is an advantage.
• Excellent English skills written and spoken
• Highly motivated and ambitious candidates are encouraged to apply. The position requires solid previous work experience from an established research laboratory or private company.
• A solution-oriented, organizational and positive mindset is required. The ability to work in a highly collaborative international environment both independently and as part of the team is essential.

We offer:

• A stimulating, challenging and multifaceted research environment
• A supportive team to work and collaborate with
• A combination of exciting projects and state-of-the-art technologies to expand your horizons
• Possibilities for continued education and training
• Attractive employment conditions
• Centrally located workplace

Place of employment
The place of employment is at the NNF ReNEWt, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment.

Terms of salary, work, and employment:
The position is a fixed-term position limited to a period of 2 years, and the average weekly working hours are 37 hours per week.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” 2020.

Questions:
For further information contact Associate Professor Kim Bak Jensen,[email protected]

Foreign applicants may find the following links useful: www.ism.ku.dk (International Staff Mobility) and www.workingconditions.ku.dk.

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Deadline for applications: 3 December 2024, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

We want to reflect the surrounding society and encourage all qualified persons, regardless of personal background, to apply for the position.