Postdoc position in NMR-based mechanistic biochemistry

Are you interested in NMR-based structural mechanistic biology and excited at the prospect to contribute to the molecular understanding of the human longevity factor FoxO3? Then the Viennet lab at iNANO invites you to apply for a fulltime 2.5-year Postdoc position funded by the Independent Research Fund Denmark.
 

Expected start date and duration of employment

This is a 2.5–year position from 1 October 2024 or as soon possible thereafter. 
 

Job description

The position will focus on experimental determination of mechanisms underlying the regulation of FoxO3 by phosphorylation. Two main aspects will be investigated, namely the regulation of co-activator binding and DNA interactions.
 You will establish protocols and prepare specifically phosphorylated samples of FoxO3, and perform NMR, biophysical and cell biology experiments. The focus can be put on advanced chemical biology routes or advanced dynamics NMR experiments, depending on your interests. 
 If your interests align, you will contribute to the development of novel tailored NMR methods. You will work closely with international collaborators, including through a research stay abroad at IBS Grenoble or Brown University.

You will present your research at local and international conferences. 

Your profile

• Applicants should hold a PhD in structural biology, chemical biology or similar.
• Applicants must have good skills in English (oral and written) and be independent, creative, and dependable.
• Applicants should have several publications in internationally recognized peer-reviewed journals, experience in presenting their work and strong personal and team-work skills. Demonstrated experience working in large collaborative environments and contributing to lab management is a plus.
• Priority will be given to applicants with a previous experience in NMR OR chemical biology approaches to protein phosphorylation.

Who we are

The Interdisciplinary Nanoscience Center (iNANO; inano.au.dk) at Aarhus University is a modern research and education center with a particular emphasis on collaboration across traditional disciplinary boundaries. iNANO is at the forefront of nanocharacterization and is equipped with state-of-the-art facilities in microscopy, diffraction, spectroscopy and cell culture. The NMR research is also embedded within the Department of Chemistry (chem.au.dk).

The Viennet lab in the bioNMR group focuses on elucidating protein regulation by NMR and investigates protein disorder, dynamics and interactions. We are part of the Danish Center for Ultra-high field NMR spectroscopy and have access to NMR spectrometers operating at 500, 700 and 950 MHz for solution NMR, as well as solid-state spectrometers.

More information can be found at:https://inano.au.dk/about/research-centers-and-projects/nmr/Aarhus University provides a strong international research and training environment with excellent professional and private conditions. Foreign employees can get help and information from the AU International Center (au.dk/en/internationalcentre) and Work in Denmark (workindenmark.dk). Tax reduction schemes for researchers may apply. 

What we offer

The iNANO center offers:

• A well-developed research infrastructure, laboratories and access to shared equipment
• An exciting interdisciplinary environment with many national, international and industrial collaborators
• A research climate encouraging lively, open and critical discussion within and across different fields of research
• A work environment with close working relationships, networking and social activities
• A workplace characterised by professionalism, equality and a healthy work-life balance.

Place of work and area of employment

The place of work is the iNANO house, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark, and the area of employment is Aarhus University with related departments.  

Contact information

For further information, please contact: Assist. Prof. Thibault Viennet by email at [email protected].  

Deadline

Applications must be received no later than 12 August 2024.


Application procedure

Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline. Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

Formalities and salary range

Natural Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.

The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.

Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.

Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.

Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.

At the Faculty of Natural Science at Aarhus University, we strive to support our scientific staff in their career development. We focus on competency development and career clarification and want to make your opportunities transparent. On our website, you can find information on all types of scientific positions, as well as the entry criteria we use when assessing candidates. You can also read more about how we can assist you in your career planning and development.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.


Aarhus University

Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at www.international.au.dk/