The Center for Endotheliomics applies various techniques including bioinformatic analysis of clinical metabolomics to understand the endothelial pathology in various conditions including pulmonary hypertension, sepsis, and traumatic shock. The Center is seeking a master student to perform a meta-analysis of several clinical metabolomics data sets in order to better understand the disease agnostic metabolic links to markers of endothelial dysfunction in these diseases.
The job This group seeks a master student who has some experience of cell culture or fluorescent microscopy or molecular biology techniques. This person will culture vascular endothelial cells and perform various cell and molecular biology analyses.
- Culture of vascular endothelial cells. Knowledge of standard sterile cell culture techniques is useful.
- Immunofluorescent microscopy. We will use immunocytochemistry to stain cells with fluorescent antibodies to monitor the changes in protein expression and localization with regards to the stimuli.
- Other cell and molecular biology assays. We will stimulate cells with inflammatory mediators, drugs or alter the expression of proteins of interest. We will also use some other techniques such as western blotting and qPCR, plate based biochemical assays and Seahorse metabolic analyzer to monitor these cells.
About us An established inter-disciplinary group of clinicians, bioinformaticians and wet-lab biologists taking a data driven approach to the biology underlying endothelial dysfunction that contributes to a variety of diseases. This is a bench to bedside group with collaborations both in Europe and the USA.
About you You are the right candidate if you are:
• A Master student in Cell biology, Molecular Biology, Biochemistry or similar or a Medical Student with previous cell culture experience. Some previous cell or molecular biology laboratory experience is necessary. However, this position will provide an opportunity to build on this experience.
• Knowledge of cardiovascular disease and acute critical illness, cell metabolism or vascular biology would be an advantage.
As a person, you can collaborate and create relationships that cross traditional disciplinary boundaries between clinicians, biologists and computational analysts.
Terms of employment The employment as a Student Research Assistant is a 15 hour per week position for 9 months. Starting date is 1st of February 2025, or after agreement.
Salary, pension, and terms of employment will be in accordance with the current agreement in The Capital Region of Denmark. Depending on qualifications, a supplement may be negotiated.
The work will take place at the Copenhagen University Hospital, Rigshospitalet, located centrally in Copenhagen, close to the medical and science campuses of the University of Copenhagen.
Application procedure If you want to know more about the position, you are welcome to contact Dr Sarah McGarrity, CAG Center for Endotheliomics, Department of Clinical Immunology, Copenhagen University Hospital - Rigshospitalet, e-mail:
[email protected] read more about the Center at:
https://gchsp.dk/cag/cag-center-for-endotheliomics/ The application deadline is 15th of January 2025.
Copenhagen University Hospital wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background or belief.
Send your application, CV and educational certificates online via the link on this page.